Autism and Vaccines

We still don’t know what causes autism, but we have learned what doesn’t cause it.  Numerous studies have failed to show a link between autism and vaccines. 

Jan 2010: A new website sponsored by non profit organization Every Child By Two offers video responses to frequently asked questions about autism and vaccines. The site features several experts including ASF board member Dr. Paul Offit and ASF President Alison Singer. Visit this site.
Read the Science
Literature Reviews: Autism and Vaccines
"Vaccines and Autism: A Tale of Shifting Hypotheses"
--Clinical Infectious Diseases, Offit, Paul and Gerber, Jeffrey S. (Feb. 2009)
"Immunization Safety Review: Vaccines and Autism"
--Institute of Medicine (May 2004)
Too Many Too Soon?

"Addressing Parents' Concerns: Do Multiple Vaccines Overwhelm or Weaken the Infant's Immune System?"
- Pediatrics, Offit, Paul A., Quarles, Jessica, et al. (2002)

"Immunization Safety Review: Multiple Immunizations and Immune Dysfunction"
--Institute of Medicine (Feb. 2002)

"Cellular Immune Responses in Neonates"
- International Reviews of Immunology, Fadel S, Sarazotti M. (2000)

"Neonatal and Early Life Vaccinology"
- Vaccine, Siegrist CA. (2001)

 "The Problem with Dr. Bob's Alternative Vaccine Schedule"
- Pediatrics, Offit, Paul A. and Moser, Charlotte A. (January 2009)

Thimerosal and Autism Studies

Neuropsychological performance 10 years after immunization in infancy with thimerosal-containing vaccines. --Pediatrics, Tozzi AE, Bisiacchi P, Tarantino V, De Mei B, D'Elia L, Chariotti F, Salmaso S. (January 2009)

Continuing Increases in Autism Reported to California's Developmental Services System — Archives of General Psychiatry, Robert Schechter, MD, MSc and Judith K. Grether, PhD (January 2008)

"Early Thimerosal Exposure and Neuropsychological Outcomes at 7 to 10 Years" — New England Journal of Medicine, Thompson WW, Price C, Goodson B, et al. (September, 2007)

“Lack of Association Between Rh Status, Rh Immune Globulin in Pregnancy and Autism” — American Journal of Medical Genetics, Judith H. Miles and T. Nicole Takahashi (May 2007)

"Comparison of Blood and Brain Mercury Levels in Infant Monkeys Exposed to Methylmercury or Vaccines Containing Thimerosal"
– Environmental Health Perspectives, Thomas M. Burbacher, PhD (April 2005)

"Thimerosal Exposure in Infants and Developmental Disorders: A Prospective Cohort Study in the United Kingdom Does Not Support a Causal Association"
– Pediatrics, John Heron and Nick Andrews, PhD and Jean Golding, DSc (September 2004)

"Neurotoxic Effects of Postnatal Thimerosal Are Mouse Strain Dependent"
– Molecular Psychiatry, M Hornig, MD (June 2004)

"Safety of Thimerosal-Containing Vaccines: A Two-Phased Study of Computerized Health Maintance Organization Database"
- Pediatrics, Thomas Verstraeten, MD (November 2003)

"Association Between Thimerosal-Containing Vaccine and Autism"
– Journal of the American Medical Association, Anders Hviid, MSc (October 2003)

"Thimerosal and the Occurrence of Autism: Negative Ecological Evidence from Danish Population-Based Data"
– Pediatrics, Kreesten M. Madsen, MD (September 2003)

"Autism and Thimerosal-Containing Vaccines: Lack of Consistent Evidence for an Association"
– American Journal of Preventive Medicine, Paul Stehr-Green, DrPh, MPH (August 2003)

"Thimerosal and Autism?"
– Pediatrics, Karen Nelson, MD (March 2003)

"Mercury concentrations and metabolism in infants receiving vaccines containing thiomersal: A descriptive study"
– The Lancet, Michael Pichichero, MD (November 2002)

Measles-Mumps-Rubella (MMR) Vaccine and Autism Studies

"Lack of Association Between Measles Virus Vaccine and Autism with Enteropathy: A Case-Control Study"
-PLoS One, Hornig M, Briese T, Buie T, Bauman ML, Lauwers G, et al. (September 2008)

"Measles Vaccination and Antibody Response in Autism Spectrum Disorders"
-Archives of Disease in Childhood, Gillian Baird, F.R.C.Paed. (February 2008)

"Pervasive Developmental Disorders in Montreal, Quebec, Canada: Prevalence and Links With Immunizations"
-Pediatrics, Eric Fombonne, MD (Volume 118, Number 1, July 2006)

"MMR Vaccination and Pervasive Developmental Disorders: A Case-Control Study"
– The Lancet, Liam Smeeth, MRCGP (September 11, 2004)

"Association of Autistic Spectrum Disorder and the Measles, Mumps, and Rubella Vaccine"
– Archives of Pediatrics & Adolescent Medicine, Kumanan Wilson, MD, MSc, FRCP (July 2003)

"Neurologic Disorders After Measles-Mumps-Rubella Vaccination"
– Pediatrics, Annamari Makela, MD (Volume 110, Number 5, November 2002)

"No Evidence for a New Variant of Measles-Mumps-Rubella-Induced Autism"
– Pediatrics, Eric Fombonne, FRCPsych (Volume 108, Number 4, October 2001)

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