Autism Research

FMR1 Knockout Mice Observed to have Hyperactive Neural Firing Rates

Source: 
Nature: Neuroscience
Date Published: 
June 2, 2013
Abstract: 

Researchers at UCLA observed hyperactive firing rates in the brains of FMR1 knockout mice; mice engineered to have symptoms similar to those in ASD and Fragile X syndrome.

New Gene Variants Linked to Autism

Source: 
Nature
Date Published: 
May 28, 2013
Abstract: 

A new study using families from the Autism Genetic Resource Exchange (AGRE) finds that individuals with autism are 20% more likely to have copy-number variations of specific genes.

Seaside Therapeutics Discontinues Arbaclofen (STX209) Extension Study

Source: 
The Boston Globe
Date Published: 
May 31, 2013
Abstract: 

Seaside Therapeutics has discontinued their extension study of Arbaclofen (STX209), a drug that showed promise in treating social impairment related to Fragile X syndrome.

Brain Responses to Words in 2-Year-Olds with Autism Predict Developmental Outcomes at Age 6

Source: 
PLoS ONE
Date Published: 
May 29, 2013
Abstract: 

Researchers have demonstrated that brain responses to words in children with autism at age two may strongly predict cognitive ability, receptive language and adaptive behavior in those children at ages 4 and 6.

Compared to What? Early Brain Overgrowth in Autism and the Perils of Population Norms

Source: 
Biological Psychiatry
Date Published: 
May 23, 2013
Abstract: 

A new report questions the evidence for atypical early brain growth in ASD, suggesting reports of abnormal head circumference (HC) growth may be due to a systematic bias in common HC norms rather than dysregulated early brain growth in ASD. The authors encourage future studies to use comparison data from typically developing and clinical control samples and several growth norms in parallel to avoid bias.

SFARI Live DSM-5 Discussion: May 29 3pm ET

Source: 
SFARI
Date Published: 
May 23, 2013
Abstract: 

Simons Foundation will host a live DSM-5 roundtable discussion on May 29 at 3pm ET. The panelists, Dr. Thomas Insel, Dr. Cathy Lord and Dr. Helen Tager-Flusberg, will explore the new guidelines' impact on autism diagnosis as well as on research. Listeners will have a chance to ask the panelists questions during the discussion.

At the event time, call 866-740-1260 (access code: 2979382) to listen to the live discussion. To follow the live chat and submit your own questions, log in to readytalk.com using the access code 2979382.

Environmental Enrichment as an Effective Treatment for Autism: A Randomized Controlled Trial

Source: 
Behavioral Neuroscience
Date Published: 
May 20, 2013
Abstract: 

Researchers at University of California Irvine conducted a randomized controlled trial of sensorimotor enrichment in young boys with ASD. Behavioral and cognitive improvements in the children who received sensorimotor therapy suggest that it may be a promising treatment for ASD symptoms. The group is now conducting a larger trial that includes girls.

A Substantial and Unexpected Enhancement of Motion Perception in Autism

Source: 
Journal of Neuroscience
Date Published: 
May 8, 2013
Abstract: 

This new study found that children with autism see simple movement twice as quickly as other children their age.

Autism Matters Podcast Series

Source: 
Autism
Date Published: 
May 13, 2013
Abstract: 

The Autism Matters podcast series aims to showcase the latest research published in the journal Autism in a way that is accessible, easy to understand and has real world relevance. The podcasts are aimed at a broad audience, including academics, researchers, students, clinicians, journalists, policy makers, individuals with autism and their families, and anyone interested in autism spectrum disorders.