Autism Science

Prefrontal Neuromodulation Using rTMS Improves Error Monitoring and Correction Function in Autism

Source: 
Appl Psychophysiol Biofeedback
Date Published: 
June, 2012
Year Published: 
2012
Abstract: 

The goal of this study was to investigate whether reaction time, error rate, post-error reaction time change, error related negativity, and error related positivity will show positive changes following 12-week long slow frequency repetitive Transcranial Magnetic Stimulation(rTMS) over dorsolateral prefrontal cortex (DLPFC) in high functioning children with ASD.

Effects of Risperidone and Parent Training on Adaptive Functioning in Children with Pervasive Developmental Disorders and Serious Behavioral Problems

Source: 
J Am Acad Child Adolesc Psychiatry
Date Published: 
February, 2012
Year Published: 
2012
Abstract: 

Children with Pervasive Developmental Disorders (PDDs) have social interaction deficits, delayed communication, and repetitive behaviors as well as impairments in adaptive functioning. Many children actually show a decline in adaptive skills compared with age mates over time.

Design and Subject Characteristics in The Federally-Funded Citalopram Trial in Children with Pervasive Developmental Disorders

Source: 
J Autism Dev Disord
Date Published: 
March, 2012
Year Published: 
2012
Abstract: 

This study conducted a randomized trial with citalopram (an anti-depressant drug) in children with Pervasive developmental disorders (PDDs).

Effects of a Brief Early Start Denver Model (ESDM)-Based Parent Intervention on Toddlers at Risk for Autism Spectrum Disorders: A Randomized Controlled Trial

Source: 
J Am Acad Child Adolesc Psychiatry
Date Published: 
October, 2012
Year Published: 
2012
Abstract: 

This study was carried out to examine the efficacy of a 12-week, low-intensity, parent-delivered intervention for toddlers at risk for autism spectrum disorders (ASD) aged 14 to 24 months and their families.

Cholesterol connection to Rett Syndrome

Source: 
Nature Genetics
Date Published: 
July 28, 2013
Abstract: 

Professor Monica Justice has written a study on a connection between cholesterol and Rett Syndrome. Statin drugs, known to lower cholesterol, were shown to increase mobility, overall health scores, and lifespan in mice with Rett Syndrome.

Group Cognitive Behavior Therapy for Children with High-Functioning Autism Spectrum Disorders and Anxiety: A Randomized Trial

Source: 
J Child Psychol Psychiatry
Date Published: 
April, 2012
Year Published: 
2012
Abstract: 

Fifty children with high-functioning Autism Spectrum Disorder (ASD) and anxiety were randomized to group Cognitive Behavioral Theory (CBT) or treatment-as-usual (TAU) for 12 weeks.

Melatonin for Sleep in Children with Autism: A Controlled Trial Examining Dose, Tolerability, and Outcomes

Source: 
J Autism Dev Disord
Date Published: 
August, 2012
Year Published: 
2012
Abstract: 

Supplemental melatonin has shown promise in treating sleep onset insomnia in children with autism spectrum disorders (ASD).

Teacher-Implemented Joint Attention Intervention: Pilot Randomized Controlled Study for Preschoolers with Autism

Source: 
J Consult Clin Psychol
Date Published: 
August, 2012
Year Published: 
2012
Abstract: 

This study investigated the effectiveness of public preschool teachers implementing a validated intervention (the Joint Attention and Symbolic Play/Engagement and Regulation intervention; JASP/ER) on a core deficit of autism, initiating joint attention.

The Effect of Levetiracetam on Focal Nocturnal Epileptiform Activity During Sleep-A Placebo-Controlled Double-Blind Cross-Over Study

Source: 
Epilepsy Behav
Date Published: 
May, 2012
Year Published: 
2012
Abstract: 

This study was designed to assess AED effect in a placebo-controlled double-blind cross-over study. Levetiracetam (LEV) was chosen based on clinical evidence.

Making the Connection: Randomized Controlled Trial of Social Skills at School for Children with Autism Spectrum Disorders

Source: 
J Child Psychol Psychiatry
Date Published: 
April, 2012
Year Published: 
2012
Abstract: 

This study compared two interventions for improving the social skills of high functioning children with autism spectrum disorders in general education classrooms. One intervention involved a peer-mediated approach (PEER) and the other involved a child-assisted approach (CHILD).