Autism Science

Genetic Variations in Chromosome 16 Region Affect More Males with Autism Than Females

Source: 
PLoS One
Date Published: 
April 18, 2013
Abstract: 

London study finds a higher rate of gene variations in the chromosome 16 region in males with autism compared to females.

Studies Show Key Steps of How Mutations to the MeCP2 Gene Cause Rett Syndrome

Source: 
Nature Neuroscience
Date Published: 
June 16, 2013
Abstract: 

Two collaborative papers reveal the key steps of how mutations to the MeCP2 gene cause Rett Syndrome by impairing the interaction between MeCP2 and the NCoR/SMRT co-repressor.

Fragile X Mutation May Produce Toxic Protein Clumps That Cause FXTAS

Source: 
Neuron
Date Published: 
May 8, 2013
Abstract: 

University of Michigan study finds that a mild form of the fragile X mutation produces protein clumps that may trigger fragile X-associated tremor/ataxia.

Perinatal Exposure to Air Pollutants May Increase Risk for ASD.

Source: 
Environmental Health Perspectives
Date Published: 
June 18, 2013
Abstract: 

Study finds correlation that suggests that women who are exposed to high levels of air pollution during pregnancy have a higher chance of having a child with autism.

Voices May Not Trigger Brain's Reward Centers in Children with ASD

Source: 
PNAS
Date Published: 
June 17, 2013
Abstract: 

This Stanford study identifies an underconnectivity between the voice-selective cortex and the reward centers in the brain. This could suggest why children with autism have trouble grasping the social and emotional aspects of human speech.

Brain Imaging Reveals Thicker Cortex with More Folds in Autism Brains

Source: 
Brain: A Journal of Neurology
Date Published: 
June 2013
Abstract: 

Brain imaging study reveals individuals with autism have a ticker cortex with more folds. This suggests that differences in cognitive abilities of people with autism could be due to unique brain structures.

Meta-Analysis of The Effects of Risperidone or Aripiprazole on Individuals with ASD

Source: 
Research in Autism Spectrum Disorders
Date Published: 
January 2013
Abstract: 

This study analyzes the efficacy and secondary effects of the drugs, Risperidone and Aripipazole.

Arboclofen Has Potential to Improve Social Function and Behavior in Patients with Fragile X Syndrome

Source: 
Science Translational Medicine
Date Published: 
September 9, 2012
Abstract: 

Research on animal models suggests that STX209 (arboclofen) might improve neurobehavioral function in patients affected with Fragile X Syndrome.

PCBs Identified as Possible Environmental Risk Factor Contributing to Autism

Source: 
Environmental Health Perspectives
Date Published: 
July 12, 2012
Abstract: 

Study identifies Polychlorinated Biphenyl (PCB), which are widely used as dielectric and coolant fluids, as a candidate environmental risk factor for neurodevelopmental disorders, including autism.

First Prospective Study on the Effect of Shank3 Deficiency on Phelan-McDermid Syndrome

Source: 
Molecular Autism
Date Published: 
June 11, 2013
Abstract: 

ASF Scientific Advisory Board Member, Joe Buxbaum, directed the first prospective study on the effects of Shank3 deficiency on a subtype of autism called 22q13 Deletion Syndrome, also known as Phelan-McDermid Syndrome.