Autism Science

Respite Care, Marital Quality, and Stress in Parents of Children with Autism Spectrum Disorders

Source: 
Journal of Autism and Developmental Disorders
Date Published: 
March 2013
Abstract: 

In a new study looking at parents of children with ASD, researchers found that parents were less stressed and had improved marital quality with each hour of respite care received.

Frequency and Pattern of Documented Diagnostic Features and the Age of Autism Identification

Source: 
Journal of the American Academy of Child & Pediatric Psychiatry
Date Published: 
February 6, 2013
Abstract: 

The age at which a child with autism is diagnosed is related to the particular suite of behavioral symptoms he or she exhibits, according to this study led by an ASF Grantee. Certain diagnostic features, including poor nonverbal communication and repetitive behaviors, were associated with earlier identification of an autism spectrum disorder. Displaying more behavioral features was also associated with earlier diagnosis.

For more information about this study, read the guest blog from the lead author here: http://autismsciencefoundation.wordpress.com/2013/04/09/identifying-asd-...

Live Chat with Dr. Simon Baron-Cohen

Source: 
ASF
Date Published: 
April 5, 2013
Abstract: 

Did you miss the live chat? Read the transcript here.

Global Increases in Both Common and Rare Copy Number Load Associated with Autism

Source: 
Human Molecular Genetics
Date Published: 
March 27, 2013
Abstract: 

Penn State researchers link autism to increased genetic change in "hotspots", regions of the genome that are highly susceptible to mutation.

Increasing Exposure to Antibody-Stimulating Proteins and Polysaccharides in Vaccines Is Not Associated with Risk of Autism

Source: 
Journal of Pediatrics
Date Published: 
March 6, 2013
Abstract: 

This CDC study casts further doubt on the link between autism and vaccines. The study found no connection between the number of vaccines received and autism risk.

Autism Risk Across Generations A Population-Based Study of Advancing Grandpaternal and Paternal Age

Source: 
JAMA Psychiatry
Date Published: 
March 20, 2013
Abstract: 

Recently published in JAMA Psychiatry, this study put forth a new autism risk factor: advanced grandpaternal age. Compared to men who had children between 20 and 24, men who fathered a child at 50+ were 1-2 times more likely to have a grandchild with autism. The findings suggest some autism risk factors can accumulate over generations.

A Quantitative Link between Face Discrimination Deficits and Neuronal Selectivity for Faces in Autism

Source: 
NeuroImage: Clinical
Date Published: 
March 15, 2013
Abstract: 

In this fMRI study of adults with ASD, reduced neuronal selectivity for faces was linked to greater behavioral deficits in face recognition.

Tipping the balance of autism risk: potential mechanisms linking pesticides and autism.

Source: 
PubMed
Date Published: 
July 2012
Abstract: 

In animal studies, we encourage more research on gene × environment interactions, as well as experimental exposure to mixtures of compounds. Similarly, epidemiologic studies in humans with exceptionally high exposures can identify which pesticide classes are of greatest concern, and studies focused on gene × environment are needed to determine if there are susceptible subpopulations at greater risk from pesticide exposures.

Maternal periconceptional folic acid intake and risk of autism spectrum disorders and developmental delay in the CHARGE (CHildhood Autism Risks from Genetics and Environment) case-control study.

Source: 
PubMed
Date Published: 
July 2012
Abstract: 

Folic acid may reduce ASD risk in those with inefficient folate metabolism. The replication of these findings and investigations of mechanisms involved are warranted.

Advancing maternal age is associated with increasing risk for autism: a review and meta-analysis.

Source: 
PubMed
Date Published: 
May 2012
Abstract: 

Results of this meta-analysis support an association between advancing maternal age and risk of autism. The RR increased monotonically with increasing maternal age. The association persisted after the effects of paternal age and other potential confounders had been considered, supporting an independent relation between higher maternal age and autism.