Diagnosis

Frequency and Pattern of Documented Diagnostic Features and the Age of Autism Identification

Source: 
Journal of the American Academy of Child & Pediatric Psychiatry
Date Published: 
February 6, 2013
Abstract: 

The age at which a child with autism is diagnosed is related to the particular suite of behavioral symptoms he or she exhibits, according to this study led by an ASF Grantee. Certain diagnostic features, including poor nonverbal communication and repetitive behaviors, were associated with earlier identification of an autism spectrum disorder. Displaying more behavioral features was also associated with earlier diagnosis.

For more information about this study, read the guest blog from the lead author here: http://autismsciencefoundation.wordpress.com/2013/04/09/identifying-asd-...

Changes in Prevalence of Parent-reported Autism Spectrum Disorder in School-aged U.S. Children: 2007 to 2011–2012

Source: 
CDC
Date Published: 
March 20, 2013
Abstract: 

This report presents data on the prevalence of diagnosed autism spectrum disorder (ASD) as reported by parents of school-aged children (ages 6–17 years) in 2011–2012. Results suggest 1 in 50 U.S. children is diagnosed with ASD based on parent report.

Evaluating Changes in the Prevalence of the Autism Spectrum Disorders (ASDs)

Source: 
Public Health Reviews
Date Published: 
March 14, 2013
Abstract: 

In effort to stimulate more research to better understand ASD trends, ASF President Alison Singer and other stakeholders discuss the increase in ASD prevalence and share their knowledge and opinions.

Autism Spectrum Disorder Reclassified: A Second Look at the 1980s Utah/UCLA Autism Epidemiologic Study

Source: 
Journal of Autism and Developmental Disorders
Date Published: 
January 1, 2013
Abstract: 

According to this study, DSM-IV-TR criteria capture more individuals with ASD and intellectual disability than DSM III criteria. The authors examined records from a statewide epidemiological study in the 80s and found that 59% of participants who were considered ‘not autistic’ in the original study likely were autistic based on current DSM criteria and clinician review methods used in CDC studies.

The Modified Checklist for Autism in Toddlers: Reliability in a Diverse Rural American Sample

Source: 
Journal of Autism and Developmental Disorders
Date Published: 
February 6, 2013
Abstract: 

Researchers at Virginia Tech examine M-CHAT performance in a very low socio-economic status setting and find it lacks internal consistency across ethnic and educational groups. Caregivers who reported a low maternal educational level or with minority status were more likely to mark items suggestive of autism compared to those with higher maternal education or non-minority status

How Different Are Girls and Boys Above and Below the Diagnostic Threshold for Autism Spectrum Disorders?

Source: 
Journal of the American Academy of Child and Adolescent Psychiatry
Date Published: 
August 2012
Abstract: 

A study finds that despite showing similar autistic traits, girls are less likely than boys to meet diagnostic criteria for ASD if no other intellectual or behavioral issues are present. The authors suggest the results might reflect biased diagnosis or better adaptation in girls.

Age at Diagnosis of Autism Spectrum Disorders

Source: 
Journal of Pediatrics
Date Published: 
June 9, 2012
Abstract: 

"Early identification of autism has become a national priority but, despite efforts, there are children who are being identified at a later age. In this study, children of Hispanic and African American origin, foreign-born children, and children born to foreign mothers were more likely to be diagnosed later."

The First Year Inventory: A Longitudinal Follow-up of 12-month-old to 3-year-old Children

Source: 
Autism
Date Published: 
August 2, 2012
Abstract: 

"The First Year Inventory is a parent-report measure designed to identify 12-month-old infants at risk for autism spectrum disorder. First Year Inventory taps behaviors that indicate risk in the developmental domains of sensory-regulatory and social-communication functioning. This longitudinal study is a follow-up of 699 children at 3 years of age from a community sample whose parents completed the First Year Inventory when their children were 12 months old. Parents of all 699 children completed the Social Responsiveness Scale-Preschool version and the Developmental Concerns Questionnaire to determine age 3 developmental outcomes. In addition, children deemed at risk for autism spectrum disorder based on liberal cut points on the First Year Inventory, Social Responsiveness Scale-Preschool, and/or Developmental Concerns Questionnaire were invited for in-person diagnostic evaluations. We found 9 children who had a confirmed diagnosis of autism spectrum disorder from the sample of 699. Receiver operating characteristic analyses determined that a two-domain cutoff score yielded optimal classification of children: 31% of those meeting algorithm cutoffs had autism spectrum disorder and 85% had a developmental disability or concern by age 3. These results suggest that the First Year Inventory is a promising tool for identifying 12-month-old infants who are at risk for an eventual diagnosis of autism spectrum disorder."

Predicting the Diagnosis of Autism Spectrum Disorder Using Gene Pathway Analysis

Source: 
Molecular Psychiatry
Date Published: 
September 11, 2012
Abstract: 

"The current investigation interrogated single-nucleotide polymorphisms (SNPs) of individuals with ASD from the Autism Genetic Resource Exchange (AGRE) database. SNPs were mapped to Kyoto Encyclopedia of Genes and Genomes (KEGG)-derived pathways to identify affected cellular processes and develop a diagnostic test. "