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Autism Developmental Delay Begins After 6 Months of Age

Source: 
Psych Central
Date Published: 
October 31, 2012
Abstract: 

A large, prospective study found that children with and without ASD were developmentally similar at 6 months based on clinical tests. Lead author Dr. Rebecca Landa reported, “for those children who went on to develop autism, the earliest signs of atypical development were non-specific to autism, such as general communication or motor delay.”

Is He Being Bad? Social and Language Brain Networks during Social Judgment in Children with Autism

Source: 
PLOS One
Date Published: 
October 17, 2012
Abstract: 

This fMRI study on social judgment supports claims that autistic children may recognize socially inappropriate behavior but find it difficult to express why it’s inappropriate.

Minority Toddlers With Autism May Be More Delayed Than Affected Caucasian Peers

Source: 
Medical News Today
Date Published: 
February 23, 2012
Abstract: 

The first prospective study of ethnic differences in the symptoms of autism in toddlers shows that children from a minority background have more delayed language, communication and gross motor skills than Caucasian children with the disorder. Researchers at the Kennedy Krieger Institute concluded that subtle developmental delays may be going unaddressed in minority toddlers until more severe symptoms develop.

Structure of language pathways differs in non-verbal autism

Source: 
SFARI
Date Published: 
November 14, 2011
Abstract: 

Non-verbal children with autism show structural differences in key language areas of the brain compared with controls, according to a poster presented Saturday at the Society for Neuroscience annual meeting in Washington, D.C.

Autistic Brains Grow More Slowly

Source: 
Psych Central
Date Published: 
October 20, 2011
Abstract: 

UCLA researchers have found the connections between brain regions that are important for language and social skills grow much more slowly in boys with autism than in non-autistic children...

UCLA researchers have found the connections between brain regions that are important for language and social skills grow much more slowly in boys withautism than in non-autistic children.

A Systematic Review of Early Intensive Intervention for Autism Spectrum Disorders

Source: 
Pediatrics
Date Published: 
April 2011
Year Published: 
2011

Researchers at Vanderbilt University reviewed the effectiveness of early intervention programs for children aged 12 and younger with Autism Spectrum Disorders (ASDs). Overall, the strength of the evidence ranged from insufficient to low. Studies performed at the University of California Los Angeles /Lovaas-based interventions and variants reported clinically significant gains in language and cognitive skills in some children, as did 1 randomized control trial of an early intensive developmental intervention approach (the Early Start Denver Model). Data suggests that subgroups of children displayed more prominent gains across studies, but common characteristics of those who experienced greater gains are not understood. Studies into the effectiveness of Early Intervention programs demonstrated some progress in cognitive performance, language skills, and adaptive behavior skills in some young children with ASDs, but there is limited literature available on the topic.

A Systematic Review of Secretin for Children with Autism Spectrum Disorders

Source: 
Pediatrics
Date Published: 
April 2011
Year Published: 
2011

Krishnaswami et al. Researchers at Vanderbilt University found that secretin, a medical treatment for autism spectrum disorders (ASDs) that was popularized in the 1990s, is ineffective in the treatment of ASDs. Evidence from seven randomized controlled trials suggests that secretin does not effectively treat the symptoms of ASDs, which include language and communication impairment, symptom severity, and cognitive and social deficits. Furthermore, no study conducted has found significant improvement in terms of language, cognition, or autistic symptoms when compared with placebo. The Vanderbilt researchers conclude that secretin does not have clear benefit. Additionally, since there is significant evidence of lack of impact in treating ASDs, they believe that further secretin studies should not be conducted.

New Autism Diagnostic Interview-Revised Algorithms for Toddlers and Young Preschoolers from 12 to 47 Months of Age

Source: 
J Autism Developmental Disorders, Kim et al.
Date Published: 
March 2011
Year Published: 
2011

The Autism Diagnostic Interview-Revised is a tool clinician’s use for the diagnosis of a child with an autism spectrum disorder (ASD). The diagnostic algorithms of the evaluative tool were altered to improve sensitivity and specificity compared to the previous algorithm.

Surprising View of Brain Formation: Discovery of a New Mechanism May Have Implications for a Host of Diseases

Source: 
Science Daily
Date Published: 
February 10, 2011
Abstract: 

A study from The Scripps Research Institute has unveiled a surprising mechanism that controls brain formation. In the new study, Mueller and colleagues focused on a protein called reelin. They found reelin is a key player in the migration of new nerve cells to the neocortex, the part of the brain responsible for higher-order functions, such as language and movement. The findings have implications for understanding a host of diseases, including some forms of mental retardation, epilepsy, schizophrenia, and autism.

Toddlers With Autism Show Improved Social Skills Following Targeted Intervention

Source: 
Science Daily
Date Published: 
December 9, 2010
Abstract: 

Targeting the core social deficits of autism spectrum disorders (ASD) in early intervention programs yielded sustained improvements in social and communication skills even in very young children who have ASD, according to a study funded by the National Institute of Mental Health (NIMH), part of the National Institutes of Health.