Mothers

Use of Complementary and Alternative Medicine in Children With Autism and Other Developmental Disabilities: Associations With Ethnicity, Child Comorbid Symptoms, and Parental Stress

Source: 
Journal of Child Neurology
Date Published: 
January 30, 2013
Abstract: 

Families of children with ASD and other comorbid symptoms, including behavioral problems such as irritability and food allergies, were more likely to use complementary and alternative medicine, and they were more likely to use more types of modalities as compared to families of children with other developmental disabilities.

Migration and Autism Spectrum Disorder: Population-based Study

Source: 
The British Journal of Psychiatry
Date Published: 
August 2012
Abstract: 

Results of this study show that while children of migrant parents are at an increased risk of low-functioning autism, they are at a decreased risk for high-functioning autism. Researchers call for further research to determine if environmental factors associated with migration influence the development of autism.

Elevated Maternal C-reactive Protein and Autism in a National Birth Cohort

Source: 
Molecular Psychiatry
Date Published: 
January 22, 2013
Abstract: 

Large national birth cohort study links elevated maternal C-reactive protein (a marker of systemic inflammation) to increased autism risk.

Modeling an Autism Risk Factor in Mice Leads to Permanent Immune Dysregulation

Source: 
Proceedings of the National Academy of Sciences
Date Published: 
July 31, 2012
Abstract: 

"Increasing evidence highlights a role for the immune system in the pathogenesis of autism spectrum disorder (ASD), as immune dysregulation is observed in the brain, periphery, and gastrointestinal tract of ASD individuals. Furthermore, maternal infection (maternal immune activation, MIA) is a risk factor for ASD. Modeling this risk factor in mice yields offspring with the cardinal behavioral and neuropathological symptoms of human ASD."

Placental Regulation of Maternal-fetal Interactions and Brain Development

Source: 
Developmental Neurobiology
Date Published: 
August 23, 2012
Abstract: 

"A variety prenatal insults are associated with the incidence of neurodevelopmental disorders such as schizophrenia, autism and cerebral palsy. While the precise mechanisms underlying how transient gestational challenges can lead to later life dysfunctions are largely unknown, the placenta is likely to play a key role. The literal interface between maternal and fetal cells resides in the placenta, and disruptions to the maternal or intrauterine environment are necessarily conveyed to the developing embryo via the placenta. Placental cells bear the responsibility of promoting maternal tolerance of the semiallogeneic fetus and regulating selective permeability of nutrients, gases, and antibodies, while still providing physiological protection of the embryo from adversity. The placenta's critical role in modulating immune protection and the availability of nutrients and endocrine factors to the offspring implicates its involvement in autoimmunity, growth restriction and hypoxia, all factors associated with the development of neurological complications. In this review, we summarize primary maternal-fetal interactions that occur in the placenta and describe pathways by which maternal insults can impair these processes and disrupt fetal brain development. We also review emerging evidence for placental dysfunction in the prenatal programming of neurodevelopmental disorders."

Age at Diagnosis of Autism Spectrum Disorders

Source: 
Journal of Pediatrics
Date Published: 
June 9, 2012
Abstract: 

"Early identification of autism has become a national priority but, despite efforts, there are children who are being identified at a later age. In this study, children of Hispanic and African American origin, foreign-born children, and children born to foreign mothers were more likely to be diagnosed later."

Prenatal Versus Postnatal Sex Steroid Hormone Effects on Autistic Traits in Children at 18 to 24 Months of Age

Source: 
Molecular Autism
Date Published: 
December 11, 2012
Abstract: 

Cambridge researchers are investigating the link between pre- and postnatal hormone levels and autistic traits later in life.

Exploratory Study Examines Infections, Pregnancy, Autism Risks

Source: 
USA Today
Date Published: 
November 12, 2012
Abstract: 

Study examines potential links between maternal infections during pregnancy and autism. The chief of the CDC's Developmental Disabilities Branch says "for now, the standard clinical recommendations for treating pregnant women suffering from fever or flu should not change as a result of [these] new preliminary findings."

Cognition and behavior: Fragile X Carriers Show Autism Signs

Source: 
Simons Foundation Austism Research Initiative
Date Published: 
July 27,2012
Abstract: 

According to a study published in the American Journal of Medical Genetics, Women who have a milder version of the fragile X mutation, which can lead to the full mutation in their children, have some features of autism.

The Economic Impact of Autism on Families

Source: 
The Atlantic
Date Published: 
May 31, 2012
Abstract: 

Interesting article about the financial impacts of autism on American families from The Atlantic.