Speech

Siblings of Autistic Children May Have Some Autism Related Traits, Study Says

Source: 
LA Times
Date Published: 
October 11, 2010
Abstract: 

Scientists at the Washington University School of Medicine have uncovered more evidence of a genetic basis for autism. Reviewing surveys collected from more than 1,000 families with autistic kids, they discovered that siblings of autistic children who have not been diagnosed with the disease often exhibit mild traits of autism, including speech delays.

Language Delays Found in Siblings of Children with Autism

Source: 
Medical News Today
Date Published: 
October 3, 2010
Abstract: 

A new study, led by researchers at Washington University School of Medicine in St. Louis, found mild traits, not strong enough to provoke a diagnosis of autism, seem to be present in the siblings of affected children at significantly higher rates than seen in the general population.

Siblings of children with autism have more frequent language delays and other subtle characteristics of the disorder than previously understood. Girls also may be mildly affected more often than recognized in the past.

Language as a Window into Sociability

Source: 
Science Daily
Date Published: 
August 13, 2010
Abstract: 

People with Williams syndrome-known for their indiscriminate friendliness and ease with strangers-process spoken language differently from people with autism spectrum disorders-characterized by social withdrawal and isolation-found researchers at the Salk Institute for Biological Studies.

New Technology Reveals a Unique Vocal Signature in Autism

Source: 
Medical News Today
Date Published: 
July 20, 2010
Abstract: 

Study reports new automated vocal analysis technology could fundamentally change the study of language development as well as the screening for autism spectrum disorders and language delay.

Language Dysfunction in Children May Be Due to Epilectic Brain Activity

Source: 
Science Daily
Date Published: 
April 23, 2010
Abstract: 

Epileptic activity in the brain can affect language development in children, and EEG registrations should therefore be carried out more frequently on children with severe language impairment to identify more readily those who may need medical treatment, reveals a thesis from the Sahlgrenska Academy at the University of Gothenburg.

Brain Becomes Tuned to Voices and Emotional Tone of Voice During Pregnancy

Source: 
Science Daily
Date Published: 
March 24, 2010
Abstract: 

New research finds that the brains of infants as young as 7 months old demonstrate a sensitivity to the human voice and to emotions communicated through the voice that is remarkably similar to what is observed in the brains of adults.

Music Training Enhances Brainstem Activity to Speech Sounds

Source: 
Science Daily
Date Published: 
February 22, 2010
Abstract: 

At a Feb. 20 press briefing held during the American Association for the Advancement of Science annual meeting, a Northwestern University neuroscientist argued that music training has profound effects that shape the sensory system and should be a mainstay of K-12 education. Kraus presented her own research and the research of other neuroscientists suggesting music education can be an effective strategy in helping typically developing children as well as children with developmental dyslexia or autism more accurately encode speech.

Early Intervention for Toddlers With Autism Highly Effective, Study Finds

Source: 
Science Daily
Date Published: 
November 30, 2009
Abstract: 

A novel early intervention program for very young children with autism -- some as young as 18 months -- is effective for improving IQ, language ability and social interaction, a comprehensive new study has found.

Linkage, Association, and Gene Expression Analyses Identify CNTNAP2 as an Autism-Susceptibility Gene

Source: 
American Journal of Human Genetics, Alarcon, Abrahams, et al.
Date Published: 
January 2008
Year Published: 
2008

Autism is a genetically complex neurodevelopmental syndrome in which language deficits are a core feature. We describe results from two complimentary approaches used to identify risk variants on chromosome 7 that likely contribute to the etiology of autism. A two-stage association study tested 2758 SNPs across a 10 Mb 7q35 language-related autism QTL in AGRE (Autism Genetic Resource Exchange) trios and found significant association with Contactin Associated Protein-Like 2 (CNTNAP2), a strong a priori candidate. Male-only containing families were identified as primarily responsible for this association signal, consistent with the strong male affection bias in ASD and other language-based disorders. Gene-expression analyses in developing human brain further identified CNTNAP2 as enriched in circuits important for language development. Together, these results provide convergent evidence for involvement of CNTNAP2, a Neurexin family member, in autism, and demonstrate a connection between genetic risk for autism and specific brain structures.

Infant and Toddler Oral and Manual Motor Skills Predict Later Speech Fluency in Autism

Source: 
Journal of Child Psychology and Psychiatry, Gernsbacher, Sauer et al
Date Published: 
2008

 

Infant and toddler oral-motor and manual-motor skills inter-correlated significantly, distinguished autistic children from typically developing children, and distinguished autistic children whose current-day speech was minimally fluent, moderately fluent, and highly fluent. These results were corroborated by analysis of historical home video and verified with current-day assessment.