Compared to What? Early Brain Overgrowth in Autism and the Perils of Population Norms

Biological Psychiatry
Date Published: 
May 23, 2013

A new report questions the evidence for atypical early brain growth in ASD, suggesting reports of abnormal head circumference (HC) growth may be due to a systematic bias in common HC norms rather than dysregulated early brain growth in ASD. The authors encourage future studies to use comparison data from typically developing and clinical control samples and several growth norms in parallel to avoid bias.