Deleted Genes Offer Autism Clues

American Journal of Human Genetics
Date Published: 
October 3, 2013

Research published in the American Journal of Human Genetics found that people with ASDs often have just one copy of certain genes, when typically-developing people have two. This "mis-wiring" could alter the activity of nerve cells in the brain. The study found that the most commonly missing genes were linked to autophagy - a kind of waste-disposal and renewal process for cells. This study was led by Dr. Joseph Buxbaum, who is on ASF's Scientific Advisory Board.