Supplemental MaterialBlood-Based Gene Expression Signatures of Infants and Toddlers With Autism

Submitted by dawnacrawford on September 4, 2012 - 09:48
Source: 
Journal of the American Academy of Child & Adolescent Psychiatry
Link: 
http://www.sciencedirect.com/science/article/pii/S0890856712005059
Date Published: 
September 2012
Abstract: 

Dr. Eric Courchesne recently published his work he previewed at this year's IMFAR in the "Journal of the American Academy of Child & Adolescent Psychiatry."

The mRNA expression abnormalities reliably observed in peripheral blood mononuclear cells, which are safely and easily assayed in infants, offer the first potential peripheral blood–based, early biomarker panel of risk for autism in infants and toddlers. Future work should verify these biomarkers and evaluate whether they may also serve as indirect indices of deviant molecular neural mechanisms in autism.