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Oxytocin, the Brain, and Autism
Jul 30 2012
Jul 30 2013
Location:Yale Child Study Center
To examine how the hormone Oxytocin impacts social-communication, social behavior, and brain functioning in children and adolescents with ASD. Participants will come to the Child Neuroscience Lab at Yale for two visits accompanied by a parent/guardian. During one visit they will receive a single administration of Oxytocin in nasal spray form, and during the other a placebo nasal spray will be administered. Participants will then be asked to have a conversation with their parent about a fun activity they’ve had – this conversation will allow us to examine how oxytocin impacts social communication. Participants will then have a 30-minute magnetic resonance imaging (MRI) scan while watching a series of movies and viewing pictures.
Criteria for Participation:
We are looking for children and adolescents ages 7-18 years old, who have been diagnosed with an Autism Spectrum Disorder to participate in this research study. We will also need a parent to accompany them. Participants need to be in good medical health and must speak English as their first language. All participants must meet MRI safety and Oxytocin administration eligibility.
- Oxytocin/placebo nasal spray
- Magnetic Resonance Imaging (MRI) scan
- Saliva collection for genetic and hormone analyses
- Parent-Child /Adolescent Interactions
For more information about eligibility and participating, contact the Yale Autism Program's Research Intake Coordinator, Erin MacDonnell at (203) 737-3439.
Visit http://childstudycenter.yale.edu/autism/research/brain-imaging.aspx to learn more about brain imaging studies.
To learn more about what it's like to participate in an MRI, please visit http://www.yale.edu/cnl/